Understanding Your Options for NT and NIPT
Information to help you make the best choice for you and your baby.
These tests are optional. We'll help you decide together.
Screening tests check for possible risk of certain conditions.
They don't diagnose problemsâthey help us understand if more testing might be helpful.
Most screening results show low risk and provide reassurance.
Both are done in the first trimester (first three months).
An ultrasound measurement of fluid at the back of baby's neck.
Done between 11 and 14 weeks of pregnancy.
Nuchal = back of neck
Translucency = clear fluid space
We measure the fluid space using ultrasound.
All babies have some fluidâwe're looking at the thickness.
Often combined with a blood test for better accuracy.
Together, they estimate risk for chromosome differences.
Takes about 20 minutes during ultrasound visit
Non-Invasive Prenatal Testing uses your blood to analyze baby's DNA.
Can be done as early as 10 weeks of pregnancy.
Also called: cell-free DNA testing or cfDNA
A simple blood draw from your arm.
Small amounts of baby's DNA circulate in your bloodstream.
The lab analyzes this DNA to screen for chromosome differences.
Results typically ready in 7-10 days.
| Condition | What It Means |
|---|---|
| Trisomy 21 | Down syndrome (extra chromosome 21) |
| Trisomy 18 | Edwards syndrome (extra chromosome 18) |
| Trisomy 13 | Patau syndrome (extra chromosome 13) |
NIPT can screen for additional conditions depending on the test chosen
Detection rate:
About 85% for Down syndrome
False positive rate:
About 5%
Detection rate:
Over 99% for Down syndrome
False positive rate:
Less than 1%
Both are screening tests, not diagnostic tests.
Abnormal screening results need diagnostic testing to confirm.
Both tests are very safe.
NT screening: Standard ultrasoundâno risks to you or baby.
NIPT: Standard blood drawâminimal risk of bruising.
Neither test increases risk of miscarriage
A screen showing higher risk can cause worry.
You may face decisions about further testing.
Think about: What would you do with the information? Would knowing help you prepare?
There's no "right" choiceâonly what's right for you.
You can choose not to have any first trimester screening.
We'll still monitor your pregnancy with standard ultrasounds.
Go directly to amniocentesis or CVSâtests that give definite answers.
These involve small needles and carry slight risks; we can discuss if interested.
| Result | What It Means |
|---|---|
| Low Risk / Negative | Very unlikely baby has screened conditions. Most results are low risk. |
| High Risk / Positive | Increased chance, but NOT a diagnosis. We discuss diagnostic testing options. |
| Inconclusive | Test didn't give clear answer. May need to repeat or try different test. |
You're not alone. Our team supports you through every step.
All pregnant people should be offered screening or diagnostic testing, regardless of age.
Both NT and NIPT are acceptable first-line screening options.
NIPT has higher accuracy but may not be covered by all insurance.
ACOG = American College of Obstetricians and Gynecologists
SMFM = Society for Maternal-Fetal Medicine
Usually covered by insurance as part of routine prenatal care.
Coverage varies. Many insurers cover for higher-risk pregnancies.
Some labs offer self-pay pricing if not covered.
Check with your insurance before deciding.
Take time to discuss with your partner, family, or our team.
We're here to support whatever you decide.
First trimester screening gives you options and information.
Whether you choose NT, NIPT, both, or neitherâwe're with you.
Our goal: help you make informed choices that feel right for your family.
Let's discuss what would work best for you.
We're here to answer anything on your mind.